Homogenous protein programming in the mammalian left and right ventricle free walls.

@article{Phillips2011HomogenousPP,
  title={Homogenous protein programming in the mammalian left and right ventricle free walls.},
  author={Darci Phillips and Angel Aponte and Ra{\'u}l Covian and Edward B. Neufeld and Z Yu and Robert S Balaban},
  journal={Physiological genomics},
  year={2011},
  volume={43 21},
  pages={1198-206}
}
Despite identical cardiac outputs, the right (RV) and left ventricle (LV) have very different embryological origins and resting workload. These differences suggest that the ventricles have different protein programming with regard to energy metabolism and contractile elements. The objective of this study was to determine the relative RV and LV protein expression levels, with an emphasis on energy metabolism. The RV and LV protein contents of the rabbit and porcine heart were determined with… CONTINUE READING