Homogenized tissue phantoms for quantitative evaluation of subsurface fluorescence contrast.

@article{Roy2011HomogenizedTP,
  title={Homogenized tissue phantoms for quantitative evaluation of subsurface fluorescence contrast.},
  author={Mathieu Roy and Anthony T Kim and Farhan N Dadani and Brian C. Wilson},
  journal={Journal of biomedical optics},
  year={2011},
  volume={16 1},
  pages={016013}
}
The use of phantoms comprising diluted tissue homogenates with a buried capillary containing quantum dots is demonstrated as a method to investigate the optical and biophysical factors influencing the imaging of subsurface fluorescence contrast agents. Validation of the method is demonstrated using both liquid phantoms of known optical absorption and reduced scattering and Monte Carlo computer simulations of photon transport. Conclusions regarding the optimal excitation wavelength are given and… CONTINUE READING
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