Homogeneous production of feline interferon in silkworm by replacing single amino acid code in signal peptide region in recombinant baculovirus and characterization of the product.

@article{Ueda1993HomogeneousPO,
  title={Homogeneous production of feline interferon in silkworm by replacing single amino acid code in signal peptide region in recombinant baculovirus and characterization of the product.},
  author={Yoshihiro Ueda and Toshio Sakurai and Amiel Yanai},
  journal={The Journal of veterinary medical science},
  year={1993},
  volume={55 2},
  pages={251-8}
}
In a previous paper we reported that we constructed a recombinant baculovirus named BmFeIFN1 which produced recombinant feline interferon (FeIFN) in silkworm after infection. High purification of FeIFN in body fluid from the larvae revealed that two kinds of FeIFN were produced by the BmFeIFN1. The difference between the two in the NH2-terminal amino acid sequence was clarified, and two kinds of processing at different sites in FeIFN precursor were suggested. Changing one residue of the amino… CONTINUE READING