Homogeneous processing and presentation of a recombined T cell epitope in inbred mice of different non-MHC genetic background.

@article{LoMan1996HomogeneousPA,
  title={Homogeneous processing and presentation of a recombined T cell epitope in inbred mice of different non-MHC genetic background.},
  author={Richard Lo-Man and P. Martineau and M. Hofnung and Claude Leclerc},
  journal={Cellular immunology},
  year={1996},
  volume={172 2},
  pages={180-91}
}
CD4+ T cell responses are restricted by MHC class II-encoded glycoproteins which display antigen-derived peptides. Chimeric MalE proteins expressing foreign T cell epitopes represent a potent means to induce immune responses for recombinant vaccine design. Here, we studied the influence of the non-MHC genetic background and of the processing heterogeneity displayed by various APC types on the presentation of these chimeric proteins to T cells. For this purpose, the I-Ed-restricted poliovirus… CONTINUE READING

From This Paper

Figures, tables, results, connections, and topics extracted from this paper.
0 Extracted Citations
0 Extracted References
Similar Papers

Similar Papers

Loading similar papers…