Homodimeric PHD Domain-containing Rco1 Subunit Constitutes a Critical Interaction Hub within the Rpd3S Histone Deacetylase Complex*

@article{Ruan2016HomodimericPD,
  title={Homodimeric PHD Domain-containing Rco1 Subunit Constitutes a Critical Interaction Hub within the Rpd3S Histone Deacetylase Complex*},
  author={C. Ruan and Haochen Cui and C. Lee and S. Li and B. Li},
  journal={The Journal of Biological Chemistry},
  year={2016},
  volume={291},
  pages={5428 - 5438}
}
  • C. Ruan, Haochen Cui, +2 authors B. Li
  • Published 2016
  • Biology, Medicine
  • The Journal of Biological Chemistry
  • Recognition of histone post-translational modifications is pivotal for directing chromatin-modifying enzymes to specific genomic regions and regulating their activities. Emerging evidence suggests that other structural features of nucleosomes also contribute to precise targeting of downstream chromatin complexes, such as linker DNA, the histone globular domain, and nucleosome spacing. However, how chromatin complexes coordinate individual interactions to achieve high affinity and specificity… CONTINUE READING
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