Homocysteine to Hydrogen Sulfide or Hypertension

  title={Homocysteine to Hydrogen Sulfide or Hypertension},
  author={Utpal Sen and Paras K Mishra and Neetu Tyagi and Suresh C Tyagi},
  journal={Cell Biochemistry and Biophysics},
Hyperhomocysteinemia, an increased level of plasma homocysteine, is an independent risk factor for the development of premature arterial fibrosis with peripheral and cerebro-vascular, neurogenic and hypertensive heart disease, coronary occlusion and myocardial infarction, as well as venous thromboembolism. It is reported that hyperhomocysteinemia causes vascular dysfunction by two major routes: (1) increasing blood pressure and, (2) impairing the vasorelaxation activity of endothelial-derived… CONTINUE READING


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