Homocysteine strongly enhances metal-catalyzed LDL oxidation in the presence of cystine and cysteine.

Abstract

Here we show that homocysteine stimulates low density lipoprotein (LDL) oxidation at copper(II) concentrations causing only a slight oxidation of LDL lipids. LDL oxidation by homocysteine and copper(II) is further enhanced in the presence of cystine, although cystine alone does not stimulate LDL oxidation with copper(II). Similarly, a combination of… (More)

Topics

  • Presentations referencing similar topics