Homocysteine reduces endothelial progenitor cells in stroke patients through apoptosis.

@article{Alam2009HomocysteineRE,
  title={Homocysteine reduces endothelial progenitor cells in stroke patients through apoptosis.},
  author={Mohammad Murshedul Alam and Askar A Mohammad and Umar Ashfaq Shuaib and Chenxu Wang and Usman Ghani and Brenda Schwindt and Kathryn G Todd and Ashfaq Shuaib},
  journal={Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism},
  year={2009},
  volume={29 1},
  pages={
          157-65
        }
}
Homocysteine (Hcy) is a risk factor for vascular dysfunction. High levels of Hcy may result in vascular injury accelerating atherosclerosis leading to ischemia. After ischemia, endothelial progenitor cells (EPCs) migrate from bone marrow to repair damaged sites either through direct incorporation of EPCs or by repopulating mature endothelial cells. This study looks into the relationship between increased Hcy in patients with cerebrovascular disease (CVD) and EPCs. Some patients with… CONTINUE READING

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