Homocysteine-lowering trials for prevention of heart disease and stroke.

  title={Homocysteine-lowering trials for prevention of heart disease and stroke.},
  author={Robert J. Clarke},
  journal={Seminars in vascular medicine},
  volume={5 2},
Dietary supplementation with B-vitamins that lower plasma total homocysteine concentrations are expected to lower the risk of cardiovascular disease. Folic acid and vitamin B (12) lower blood homocysteine concentrations by about 25-30% in populations without folic acid fortification, but by only 10-15% in populations with fortification. In observational studies, 25% lower homocysteine is associated with about 10% less coronary heart disease (CHD) and about 20% less stroke. This review examines… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 12 extracted citations

Similar Papers

Loading similar papers…