Homocysteine levels in patients with rheumatoid arthritis treated with low-dose methotrexate.

@article{Morgan1991HomocysteineLI,
  title={Homocysteine levels in patients with rheumatoid arthritis treated with low-dose methotrexate.},
  author={Sarah L. Morgan and Joseph E. Baggott and Helga Refsum and Per Magne Ueland},
  journal={Clinical pharmacology and therapeutics},
  year={1991},
  volume={50 5 Pt 1},
  pages={
          547-56
        }
}
  • Sarah L. Morgan, Joseph E. Baggott, +1 author Per Magne Ueland
  • Published in
    Clinical pharmacology and…
    1991
  • Medicine
  • Plasma homocysteine levels were determined in patients who participated in a randomized, double-blind placebo-controlled trial of folate supplementation (1 mg/day) during methotrexate therapy for rheumatoid arthritis. Plasma and red blood cell folate levels before methotrexate therapy were significantly negatively correlated with homocysteine levels. Homocysteine levels were not significantly correlated with the initial C1 index (an assay that measures the folate status of blood mononuclear… CONTINUE READING

    Figures, Tables, and Topics from this paper.

    Paper Mentions

    INTERVENTIONAL CLINICAL TRIAL
    This study looks at how the arthritis drug methotrexate works in low doses to treat rheumatoid arthritis. (High doses of methotrexate are used to treat some types of cancer… Expand
    ConditionsAdjuvant Arthritis, Rheumatoid Arthritis
    InterventionDietary Supplement, Drug

    Citations

    Publications citing this paper.
    SHOWING 1-10 OF 12 CITATIONS

    Toward a better understanding of methotrexate.

    VIEW 1 EXCERPT
    CITES BACKGROUND

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 43 REFERENCES

    Methionine metabolism in mammals.

    Serum folate ( FA ) levels of rheumatoid arthrilis ( RA ) palients treated with methotrexate ( MTX ) or other disease - modifying antirheumatic drugs ( DMARDs ) [ Abstract ]

    • RJ Hine, GS Alarcon, WJ Koopman
    • Arthritis Rheum
    • 1990