Homocysteine-induced inhibition of nitric oxide production in platelets: a study on healthy and diabetic subjects

@article{Mutus2001HomocysteineinducedIO,
  title={Homocysteine-induced inhibition of nitric oxide production in platelets: a study on healthy and diabetic subjects},
  author={B. Mutus and R. A. Rabini and R. Staffolani and R. Ricciotti and P. Fumelli and N. Moretti and D. Martarelli and L. Mazzanti},
  journal={Diabetologia},
  year={2001},
  volume={44},
  pages={979-982}
}
  • B. Mutus, R. A. Rabini, +5 authors L. Mazzanti
  • Published 2001
  • Medicine, Biology
  • Diabetologia
  • Abstract.Aims/hypothesis: The molecular mechanisms involved in the platelet activation observed in hyperhomocysteinemia are not known. We aimed to discover if homocysteine concentrations are associated with abnormal platelet nitric oxide production in healthy and diabetic subjects. Methods: The study cohort included 28 patients with Type I (insulin-dependent) diabetes mellitus, 30 patients with Type II (non-insulin-dependent) diabetes mellitus, and 34 healthy subjects. Homocysteine plasma… CONTINUE READING
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