Homocysteine and risk of developing hypertension in men

  title={Homocysteine and risk of developing hypertension in men},
  author={Thomas S. Bowman and J. Michael Gaziano and Meir Jonathan Stampfer and Howard D Sesso},
  journal={Journal of Human Hypertension},
In cross-sectional studies, elevated homocysteine levels are associated with higher blood pressure, but it remains unclear whether plasma homocysteine is a risk factor for hypertension. In a prospective nested case-control study, participants who developed hypertension (n=396) had significantly higher levels of baseline plasma homocysteine (12.6 mol/l) than matched controls (11.8 mol/l, P=0.03); compared to those in the lowest quintile, those in the highest quintile had a crude relative risk… CONTINUE READING

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