Homocysteine- and cysteine-mediated growth defect is not associated with induction of oxidative stress response genes in yeast.

@article{Kumar2006HomocysteineAC,
  title={Homocysteine- and cysteine-mediated growth defect is not associated with induction of oxidative stress response genes in yeast.},
  author={Arun Kumar and Lijo John and Md Mahmood Alam and Ankit Gupta and Gayatri Sharma and Beena Pillai and Shantanu Sengupta},
  journal={The Biochemical journal},
  year={2006},
  volume={396 1},
  pages={61-9}
}
Intracellular thiols like cysteine, homocysteine and glutathione play a critical role in the regulation of important cellular processes. Alteration of intracellular thiol concentration results in many diseased states; for instance, elevated levels of homocysteine are considered to be an independent risk factor for cardiovascular disease. Yeast has proved to be an excellent model system for studying many human diseases since it carries homologues of nearly 40% of human disease genes and many… CONTINUE READING

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