Homocysteine, small-vessel disease, and atherosclerosis: an MRI study of 825 stroke patients.

@article{Jeon2014HomocysteineSD,
  title={Homocysteine, small-vessel disease, and atherosclerosis: an MRI study of 825 stroke patients.},
  author={Sang-Beom Jeon and Dong-Wha Kang and Jong Sung Kim and S. U. Kwon},
  journal={Neurology},
  year={2014},
  volume={83 8},
  pages={695-701}
}
OBJECTIVE We evaluated the relationship between hyperhomocysteinemia and methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and small-vessel disease (SVD) and atherosclerotic large-vessel disease (LVD) in stroke patients. METHODS A total of 825 noncardioembolic ischemic stroke patients whose plasma concentrations of total homocysteine were measured and whose MTHFR C677T polymorphism status was identified were included in this retrospective study. MRI of the brain and magnetic… CONTINUE READING