Homocysteine, B vitamins, and vascular-access thrombosis in patients treated with hemodialysis.

@article{Tamura1998HomocysteineBV,
  title={Homocysteine, B vitamins, and vascular-access thrombosis in patients treated with hemodialysis.},
  author={Tsunenobu Tamura and Suzanne M Bergman and Sarah L. Morgan},
  journal={American journal of kidney diseases : the official journal of the National Kidney Foundation},
  year={1998},
  volume={32 3},
  pages={475-81}
}
To evaluate whether increased plasma homocysteine concentrations (hyperhomocysteinemia) are associated with thrombosis of arteriovenous (AV) grafts, we determined plasma homocysteine, plasma and erythrocyte folate, plasma vitamin B12, and vitamin B6 (pyridoxal-5'-phosphate [PLP]) in 48 patients (45 black patients and three white patients) with end-stage renal disease who received hemodialysis. 5,10-Methylenetetrahydrofolate reductase (MTHFR) genotypes were also analyzed. The patients were… CONTINUE READING
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