Homochiral oligopeptides by chiral amplification: interpretation of experimental data with a copolymerization model.

  title={Homochiral oligopeptides by chiral amplification: interpretation of experimental data with a copolymerization model.},
  author={Celia Blanco and David Hochberg},
  journal={Physical chemistry chemical physics : PCCP},
  volume={14 7},
We present a differential rate equation model of chiral polymerization based on a simple copolymerization scheme in which the enantiomers are added to, or removed from, the homochiral or heterochiral chains (reversible stepwise isodesmic growth or dissociation). The model is set up for closed systems and takes into account the corresponding thermodynamic constraints implied by the reversible monomer attachments, while obeying a constant mass constraint. In its simplest form, the model depends… 
10 Citations
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