Homo obesus: a metabotrophin-deficient species. Pharmacology and nutrition insight.

@article{Chaldakov2007HomoOA,
  title={Homo obesus: a metabotrophin-deficient species. Pharmacology and nutrition insight.},
  author={George Nikov Chaldakov and Mario Fiore and Anton B. Tonchev and Dragan Dimitrov and Ruzha Pancheva and Gorana Ran{\vc}i{\vc} and Luigi Aloe},
  journal={Current pharmaceutical design},
  year={2007},
  volume={13 21},
  pages={
          2176-9
        }
}
In most countries the prevalence of obesity now exceeds 15%, the figure used by the World Health Organization to define the critical threshold for intervention in nutritional epidemics. Here we describe Homo obesus (man the obese) as a recent phenotypic expression of Homo sapiens. Specifically, we classified Homo obesus as a species deficient of metabotrophic factors (metabotrophins), including endogenous proteins, which play essential role in the maintenance of glucose, lipid, energy and… CONTINUE READING