Homo- and heterodimerization in transcriptional regulation.


Eukaryotic transcription factors bind DNA and typically serve to localize large multiprotein complexes to particular genes to up- or downregulate transcription, thereby coordinating cellular responses to a variety of signals. Different combinations of transcription factors within DNA-binding multiprotein complexes allow individual proteins to partake in… (More)
DOI: 10.1007/978-1-4614-3229-6_7


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