Homing receptors and the control of lymphocyte migration.

  title={Homing receptors and the control of lymphocyte migration.},
  author={Sirpa Jalkanen and Roger A. Reichert and W. Michael Gallatin and Robert F. Bargatze and Irving L Weissman and Eugene C. Butcher},
  journal={Immunological reviews},
The traffic of lymphocytes is controlled in part by the selective interaction of circulating lymphocytes with specialized high endothelial venule (HEV) cells at sites of lymphocyte exit from the blood. At least three independent receptor systems are responsible for controlling lymphocyte traffic to different lymphoid organs or to sites of inflammation: one mediates lymphocyte interaction with HEV in peripheral lymph nodes, another in mucosa-associated lymphoid tissues, and a third in inflamed… CONTINUE READING


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