Homing of endogenous stem/progenitor cells for in situ tissue regeneration: Promises, strategies, and translational perspectives.

@article{Chen2011HomingOE,
  title={Homing of endogenous stem/progenitor cells for in situ tissue regeneration: Promises, strategies, and translational perspectives.},
  author={Fa-Ming Chen and Li-an Wu and Min Zhang and Rong Zhang and Hai-hua Sun},
  journal={Biomaterials},
  year={2011},
  volume={32 12},
  pages={
          3189-209
        }
}
Stem cell-based therapy has been one of the best documented approaches in regenerative medicine, promising cures for a multitude of diseases and disorders. However, the ex vivo expansion of stem cells and their in vivo delivery are restricted by the limited availability of stem cell sources, the excessive cost of commercialization, and the anticipated difficulties of clinical translation and regulatory approval. An alternative to adoptively transferred stem cells are cell populations already… CONTINUE READING
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