Homer Regulates the Association of Group 1 Metabotropic Glutamate Receptors with Multivalent Complexes of Homer-Related, Synaptic Proteins
@article{Xiao1998HomerRT, title={Homer Regulates the Association of Group 1 Metabotropic Glutamate Receptors with Multivalent Complexes of Homer-Related, Synaptic Proteins}, author={Bo Xiao and Jian Cheng Tu and Ronald S. Petralia and Joseph P. Yuan and Andrew Doan and Christopher D. Breder and Alicia M. Ruggiero and Anthony A. Lanahan and Robert J. Wenthold and Paul F. Worley}, journal={Neuron}, year={1998}, volume={21}, pages={707-716} }
633 Citations
Homer Binds a Novel Proline-Rich Motif and Links Group 1 Metabotropic Glutamate Receptors with IP3 Receptors
- BiologyNeuron
- 1998
The Complex Formed by Group I Metabotropic Glutamate Receptor (mGluR) and Homer1a Plays a Central Role in Metaplasticity and Homeostatic Synaptic Scaling
- BiologyThe Journal of Neuroscience
- 2021
The constitutively active Group I mGluR-Homer1a complex is involved in the two main forms of non-Hebbian neuronal plasticity: “metaplasticity” and “homeostatic synaptic scaling,” which are implicated in a large series of physiological and pathologic processes.
Coupling of mGluR/Homer and PSD-95 Complexes by the Shank Family of Postsynaptic Density Proteins
- BiologyNeuron
- 1999
Surface clustering of metabotropic glutamate receptor 1 induced by long Homer proteins
- BiologyBMC Neuroscience
- 2005
Clusters induced by long Homers appeared on the plasma membrane and intracellularly, suggesting that clusters form prior to plasma membrane insertion and/or persist after internalization.
Homer Regulates Gain of Ryanodine Receptor Type 1 Channel Complex*
- BiologyThe Journal of Biological Chemistry
- 2002
The present work reveals a novel mechanism by which Homer directly modulates the function of its target protein RyR1 and excitation-contraction coupling in skeletal myotubes and is a direct modulator of Ca2+ release gain.
Molecular characterisation of two structurally distinct groups of human homers, generated by extensive alternative splicing.
- BiologyJournal of molecular biology
- 2000
It is discovered that extensive alternative splicing generates a family of 17 Homer proteins, which fall into two distinct groups of 12 "long" Homers, which all have a coiled-coil domain at their C termini, and five "short" Homer, which lack such a domain.
Homer 1b Regulates the Trafficking of Group I Metabotropic Glutamate Receptors*
- Biology, ChemistryThe Journal of Biological Chemistry
- 1999
It is demonstrated that Homer 1b (H1b), a constitutively expressed splice form of the immediate early gene product Homer (now termed Homer 1a) regulates the trafficking and surface expression of group I metabotropic glutamate receptors.
The Homer-1 protein Ania-3 interacts with the plasma membrane calcium pump.
- BiologyBiochemical and biophysical research communications
- 2006
Control of constitutive activity of metabotropic glutamate receptors by Homer proteins
- Biology, Chemistry
- 2003
An N-terminal sequence specific for a novel Homer1 isoform controls trafficking of group I metabotropic glutamate receptor in mammalian cells.
- Biology, ChemistryBiochemical and biophysical research communications
- 2002
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