Homer Regulates the Association of Group 1 Metabotropic Glutamate Receptors with Multivalent Complexes of Homer-Related, Synaptic Proteins

@article{Xiao1998HomerRT,
  title={Homer Regulates the Association of Group 1 Metabotropic Glutamate Receptors with Multivalent Complexes of Homer-Related, Synaptic Proteins},
  author={Bo Xiao and Jian Cheng Tu and Ronald S. Petralia and Joseph P. Yuan and Andrew Doan and Christopher D. Breder and Alicia M. Ruggiero and Anthony A. Lanahan and Robert J. Wenthold and Paul F. Worley},
  journal={Neuron},
  year={1998},
  volume={21},
  pages={707-716}
}

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TLDR
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TLDR
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The Homer-1 protein Ania-3 interacts with the plasma membrane calcium pump.
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A novel dendritic protein, Homer, is reported that contains a single, PDZ-like domain and binds specifically to the carboxy terminus of phosphoinositide-linked metabotropic glutamate receptors, suggesting that Homer mediates a novel cellular mechanism that regulates glutamate signalling.
Transcription Factor Regulation In Brain: Focus on Activity and NMDA Dependent Regulation
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A set of transcription factors that are regulated by synaptic activity and NMDA receptors and therefore may play a role in neuroplasticity are identified and examined.
Dynactin, a conserved, ubiquitously expressed component of an activator of vesicle motility mediated by cytoplasmic dynein
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It is shown that a approximately 20S polypeptide complex (referred to as Activator I) stimulates dynein- mediated vesicle transport and proposes the name dynactin (for dyne in activator), which is required for in vitro vesicles motility.
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