Homer Regulates the Association of Group 1 Metabotropic Glutamate Receptors with Multivalent Complexes of Homer-Related, Synaptic Proteins
@article{Xiao1998HomerRT, title={Homer Regulates the Association of Group 1 Metabotropic Glutamate Receptors with Multivalent Complexes of Homer-Related, Synaptic Proteins}, author={Bo Xiao and Jian Cheng Tu and Ronald S. Petralia and Joseph P. Yuan and Andrew Doan and Christopher D Breder and Alicia M Ruggiero and Anthony A. Lanahan and Robert J. Wenthold and Paul F. Worley}, journal={Neuron}, year={1998}, volume={21}, pages={707-716} }
629 Citations
Homer Binds a Novel Proline-Rich Motif and Links Group 1 Metabotropic Glutamate Receptors with IP3 Receptors
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- 1998
The Complex Formed by Group I Metabotropic Glutamate Receptor (mGluR) and Homer1a Plays a Central Role in Metaplasticity and Homeostatic Synaptic Scaling
- BiologyThe Journal of Neuroscience
- 2021
The constitutively active Group I mGluR-Homer1a complex is involved in the two main forms of non-Hebbian neuronal plasticity: “metaplasticity” and “homeostatic synaptic scaling,” which are implicated in a large series of physiological and pathologic processes.
Coupling of mGluR/Homer and PSD-95 Complexes by the Shank Family of Postsynaptic Density Proteins
- BiologyNeuron
- 1999
Surface clustering of metabotropic glutamate receptor 1 induced by long Homer proteins
- BiologyBMC Neuroscience
- 2005
Clusters induced by long Homers appeared on the plasma membrane and intracellularly, suggesting that clusters form prior to plasma membrane insertion and/or persist after internalization.
Homer Regulates Gain of Ryanodine Receptor Type 1 Channel Complex*
- BiologyThe Journal of Biological Chemistry
- 2002
The present work reveals a novel mechanism by which Homer directly modulates the function of its target protein RyR1 and excitation-contraction coupling in skeletal myotubes and is a direct modulator of Ca2+ release gain.
Molecular characterisation of two structurally distinct groups of human homers, generated by extensive alternative splicing.
- BiologyJournal of molecular biology
- 2000
It is discovered that extensive alternative splicing generates a family of 17 Homer proteins, which fall into two distinct groups of 12 "long" Homers, which all have a coiled-coil domain at their C termini, and five "short" Homer, which lack such a domain.
Homer 1b Regulates the Trafficking of Group I Metabotropic Glutamate Receptors*
- Biology, ChemistryThe Journal of Biological Chemistry
- 1999
It is demonstrated that Homer 1b (H1b), a constitutively expressed splice form of the immediate early gene product Homer (now termed Homer 1a) regulates the trafficking and surface expression of group I metabotropic glutamate receptors.
The Homer-1 protein Ania-3 interacts with the plasma membrane calcium pump.
- BiologyBiochemical and biophysical research communications
- 2006
Control of constitutive activity of metabotropic glutamate receptors by Homer proteins
- Biology, Chemistry
- 2003
An N-terminal sequence specific for a novel Homer1 isoform controls trafficking of group I metabotropic glutamate receptor in mammalian cells.
- Biology, ChemistryBiochemical and biophysical research communications
- 2002
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