Homeotic genes and the evolution of arthropods and chordates

@article{Carroll1995HomeoticGA,
  title={Homeotic genes and the evolution of arthropods and chordates},
  author={Sean B Carroll},
  journal={Nature},
  year={1995},
  volume={376},
  pages={479-485}
}
  • S. Carroll
  • Published 10 August 1995
  • Biology, Medicine
  • Nature
Clusters of homeotic genes sculpt the morphology of animal body plans and body parts. Different body patterns may evolve through changes in homeotic gene number, regulation or function. Recent evidence suggests that homeotic gene clusters were duplicated early in vertebrate evolution, but the generation of arthropod and tetrapod diversity has largely involved regulatory changes in the expression of conserved arrays of homeotic genes and the evolution of interactions between homeotic proteins… 
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Paralogous Hox genes: function and regulation.
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Functional evolution of the Ultrabithorax protein.
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  • Biology, Medicine
    Proceedings of the National Academy of Sciences of the United States of America
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Evolution: Remodelling Animal Body Plans, Gene by Gene
TLDR
A new study reveals how several mutations distributed across a gene network mask the phenotypic effects of a Hox gene's evolution.
Hox genes and study of Hox genes in crustacean
TLDR
Crustacean, presenting a variety of body plans not encountered in any other class or phylum of the Metazoa, has been shown to possess a single set of homologous Hox genes like insect.
Evolution of Chordate Hox Gene Clusters a
TLDR
It is shown that cluster duplication is consistent with a semiconservative model of duplication, where following duplication, one daughter cluster remains unmodified, while the other diverges and assumes a new architecture and presumably new functions.
Homeotic evolution in Cambrian trilobites
TLDR
A phylogenetic analysis is used to recognizeHomeotic evolution in trilobites, leading to the conclusion that homeotic evolution is common among Cambrian trilOBites.
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