Homeostatic structural plasticity – a key to neuronal network formation and repair

@inproceedings{Butz2014HomeostaticSP,
  title={Homeostatic structural plasticity – a key to neuronal network formation and repair},
  author={Markus Butz and Arjen van Ooyen},
  booktitle={BMC Neuroscience},
  year={2014}
}
Homeostasis in electrical activity is a guiding principle for network formation and reorganization throughout life. Traditionally homeostatic plasticity is thought to adapt the weight of existing synapses so that postsynaptic firing rates are regulated towards or maintained at a desired set-point. However, neither during development nor in adulthood the connectivity structure of sparsely connected brain networks is fixed but continuously rewires. Here, we summarize our most recent modeling… CONTINUE READING