Homeostatic signals do not drive post-thymic T cell maturation.

@article{Houston2012HomeostaticSD,
  title={Homeostatic signals do not drive post-thymic T cell maturation.},
  author={Evan G. Houston and Tamar E. Boursalian and Pamela J Fink},
  journal={Cellular immunology},
  year={2012},
  volume={274 1-2},
  pages={39-45}
}
Recent thymic emigrants, the youngest T cells in the lymphoid periphery, undergo a 3 week-long period of functional and phenotypic maturation before being incorporated into the pool of mature, naïve T cells. Previous studies indicate that this maturation requires T cell exit from the thymus and access to secondary lymphoid organs, but is MHC-independent. We now show that post-thymic T cell maturation is independent of homeostatic and costimulatory pathways, requiring neither signals delivered… CONTINUE READING

From This Paper

Figures, tables, results, connections, and topics extracted from this paper.
12 Extracted Citations
0 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-10 of 12 extracted citations

Similar Papers

Loading similar papers…