Homeostatic regulation of neuronal excitability by K(+) channels in normal and diseased brains.

@article{Misonou2010HomeostaticRO,
  title={Homeostatic regulation of neuronal excitability by K(+) channels in normal and diseased brains.},
  author={Hiroaki Misonou},
  journal={The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry},
  year={2010},
  volume={16 1},
  pages={51-64}
}
K(+)-selective ion channels are critical determinants of membrane excitability in neuronal cells. Like many other cells in our body, neuronal cells have a propensity to maintain their homeostasis. Action potential firing is the most important function to maintain in brain neurons, as they are the elements of neural networks. If one element fires action potentials at an abnormally high rate, the entire network could become epileptic. Therefore, brain neurons adjust their intrinsic membrane… CONTINUE READING