• DOI:10.1038/nri3049
Corpus ID: 34438005

Homeostatic chemokine receptors and organ-specific metastasis

@article{Zlotnik2011HomeostaticCR,
  title={Homeostatic chemokine receptors and organ-specific metastasis},
  author={A. Zlotnik and A. Burkhardt and B. Homey},
  journal={Nature Reviews Immunology},
  year={2011},
  volume={11},
  pages={597-606}
}

• A. Zlotnik, A. Burkhardt, B. Homey
• Published 2011
• Biology, Medicine
• Nature Reviews Immunology

It has been 10 years since the role of a chemokine receptor, CXCR4, in breast cancer metastasis was first documented. Since then, the field of chemokines and cancer has grown significantly, so it is timely to review the progress, analyse the studies to date and identify future challenges facing this field. Metastasis is the major factor that limits survival in most patients with cancer. Therefore, understanding the molecular mechanisms that control the metastatic behaviour of tumour cells is… Expand

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