Homeostatic capabilities of the choroid plexus epithelium in Alzheimer's disease

  title={Homeostatic capabilities of the choroid plexus epithelium in Alzheimer's disease},
  author={Conrad Earl Johanson and Paul N. McMillan and Rosemarie Tavares and Anthony G. Spangenberger and John A T Duncan and Gerald D. Silverberg and Edward G. Stopa},
  journal={Cerebrospinal Fluid Research},
  pages={3 - 3}
As the secretory source of vitamins, peptides and hormones for neurons, the choroid plexus (CP) epithelium critically provides substances for brain homeostasis. This distributive process of cerebrospinal fluid (CSF) volume transmission reaches many cellular targets in the CNS. In ageing and ageing-related dementias, the CP-CSF system is less able to regulate brain interstitial fluid. CP primarily generates CSF bulk flow, and so its malfunctioning exacerbates Alzheimers disease (AD… CONTINUE READING
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