© 2009 The Authors. doi: 10.2340/00015555-0580 Journal Compilation © 2009 Acta Dermato-Venereologica. ISSN 0001-5555 Sir, Homeopathy is practised in many regions of the world (1), especially in high-income countries where it ranks the most popular among traditional, complementary, or alternative medicines (1–3). One out of 5 children in a German homeopathic physicians’ practice suffered from atopic eczema (AE) (4). Meta-analyses of placebocontrolled studies including only diagnoses other than AE have shown inconsistent results (5, 6). The only randomized placebo-controlled study on AE (7) was stopped due to recruitment problems and drop-outs. In a prospective observational study we investigated the treatment and possible effects in 3981 consecutive patients (1130 children and 2851 adults) who consulted a physician for classical homeopathic therapy. This paper presents the subgroup of children with AE (ICD-9: 691.8, ICD-10: L20.8), followed up for 24 months. For more details and methods see (8).