Homeobox Genes and Their Functional Significance in Ovarian Tumorigenesis

@inproceedings{Trinh2012HomeoboxGA,
  title={Homeobox Genes and Their Functional Significance in Ovarian Tumorigenesis},
  author={Bon Quy Trinh and Honami Naora},
  year={2012}
}
It is widely recognized that many pathways that control normal embryonic patterning are deregulated in human cancers. Mutations or aberrant expression of components of the Wnt, Hedgehog and Notch signaling pathways have been demonstrated to play pivotal roles in tumorigenesis. Homeobox genes constitute an evolutionarily conserved gene super-family that represents another important class of patterning regulators. These genes encode transcription factors that are essential for controlling cell… CONTINUE READING

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