Home therapy with recombinant interleukin-2 and interferon-alpha 2b in advanced human malignancies.

@article{Atzpodien1990HomeTW,
  title={Home therapy with recombinant interleukin-2 and interferon-alpha 2b in advanced human malignancies.},
  author={Jens Atzpodien and Alfred K{\"o}rfer and Chris R. Franks and Hubert Poliwoda and Holger Kirchner},
  journal={Lancet},
  year={1990},
  volume={335 8704},
  pages={1509-12}
}
The safety, tolerance, and clinical effects of a home therapy regimen of recombinant human interleukin-2 (rIL-2) and interferon-alpha 2b (IFN-alpha 2b) self injected subcutaneously have been assessed in 35 patients with advanced cancer refractory to standard therapy. 52 treatment cycles were given, each consisting of a 2-day rIL-2 pulse of 9.0 million IU/m2 every 12 h, followed by 6 weeks of rIL-2 1.8 million IU/m2 twice daily for 5 days per week and of IFN-alpha 2b 5.0 million U/m2 thrice a… CONTINUE READING

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