Hollow fiber-liquid phase microextraction combined with gas chromatography for the determination of phenothiazine drugs in urine.

@article{Xiao2010HollowFP,
  title={Hollow fiber-liquid phase microextraction combined with gas chromatography for the determination of phenothiazine drugs in urine.},
  author={Qin Xiao and Bin Hu},
  journal={Journal of chromatography. B, Analytical technologies in the biomedical and life sciences},
  year={2010},
  volume={878 19},
  pages={1599-604}
}
A simple method of hollow fiber-liquid phase microextraction (HF-LPME) combined with gas chromatography (GC) was developed for the analysis of four phenothiazine drugs (promethazine, promazine, chlorpromazine and trifluoperazine) in human urine samples. All variables affecting the extraction of target analytes including organic solvent type, stirring rate, extraction time, extraction temperature, pH of sample solution and ionic strength were carefully studied and optimized. Under the optimal… CONTINUE READING