Hobnail variant of papillary thyroid carcinoma: an institutional case series and molecular profile.

@article{Lubitz2014HobnailVO,
  title={Hobnail variant of papillary thyroid carcinoma: an institutional case series and molecular profile.},
  author={Carrie Lubitz and Konstantinos P Economopoulos and Amanda C. Pawlak and Kerry A. Lynch and Dora C Dias-Santagata and William C. Faquin and Peter M Sadow},
  journal={Thyroid : official journal of the American Thyroid Association},
  year={2014},
  volume={24 6},
  pages={958-65}
}
BACKGROUND Papillary thyroid carcinoma (PTC) is increasing in incidence while mortality is unchanged. Identifying patients with higher risk of recurrence and death is essential. Case series identify the hobnail variant of PTC (HVPTC), which is characterized by micropapillary architecture, apocrine features, and loss of cellular polarity. Herein, we describe the clinical course, pathologic features, and mutational profile of patients at our institution with HVPTC. METHODS A query into the… CONTINUE READING

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