Immunology of Apoptosis and Necrosis
- BiologyBiochemistry (Moscow)
A complex of reactions regulating the number of cells in organs and tissues under normal and pathologic conditions is one of the most important systems of multicellular organisms. In this system,…
Chondroptosis: A variant of apoptotic cell death in chondrocytes?
The term ‘chondroptosis’ is proposed to reflect the fact that such cells are undergoing apoptosis in a non-classical manner that appears to be typical of programmed chondrocyte death in vivo, and it is speculated that the endoplasmic reticulum pathway of apoptosis plays a greater role than receptor-mediated or mitochondrial pathways and that lysosomal proteases are at least as important as caspases.
Analyzing markers of apoptosis in vitro.
- BiologyMethods in molecular biology
This chapter suggests methods to identify characteristic morphological and biochemical events, and cell-free systems that can be used to identify the molecular pathways leading to the death phenotype.
Apoptosis in Critical Illness: A Primer for the Intensivist
- BiologyIntensive Care Medicine
Recognition of the importance of apoptosis in health and disease, and an understanding of its cellular mechanisms, has increased exponentially since it was coined in 1972.
In Vivo Detection of Apoptosis
- BiologyJournal of Nuclear Medicine
The most recent developments in the biochemical characterization of the many intracellular pathways involved in this complex process are discussed and the use of MRI, MR spectroscopy, and ultrasound as possible alternative imaging modalities for the imaging of apoptosis is addressed.
Chapter 2 Apoptosis
The work on mitochondrial cristae remodelling has elucidated a novel checkpoint for apoptosis, which may determine sensitivity to apoptosis in vivo, during adult animal life.
Apoptosis: A Review of Programmed Cell Death
- BiologyToxicologic pathology
The goal of this review is to provide a general overview of current knowledge on the process of apoptosis including morphology, biochemistry, the role of apoptoses in health and disease, detection methods, as well as a discussion of potential alternative forms of apoptotic proteins.
Genetic control of necrosis - another type of programmed cell death.
- BiologyCurrent opinion in cell biology
Apoptosis effector mechanisms: A requiem performed in different keys
The molecular regulation of caspases and various caspase-independent effectors of apoptosis are discussed, the potential context and/or limitations of these mechanisms are described, and why the understanding of these processes may have relevance in cancer where treatment is believed to engage apoptosis to destroy tumor cells.
Apoptosis in selected liver diseases.
- Biology, MedicineThe Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology
The role of apoptosis in select important liver diseases is focused on and rational-based strategies are being developed to either promote or suppress apoptotic cell death as a novel therapeutic option in the treatment of these liver diseases.
SHOWING 1-10 OF 16 REFERENCES
Apoptosis: A Basic Biological Phenomenon with Wide-ranging Implications in Tissue Kinetics
- BiologyBritish Journal of Cancer
Apoptosis seems to be involved in cell turnover in many healthy adult tissues and is responsible for focal elimination of cells during normal embryonic development, and participates in at least some types of therapeutically induced tumour regression.
Apoptosis, oncosis, and necrosis. An overview of cell death.
- MedicineThe American journal of pathology
Some of the typical features of apoptosis are discussed, such as budding (as opposed to blebbing and zeiosis) and the inflammatory response, and stands in contrast to apoptosis, which leads to necrosis with karyorhexis and cell shrinkage.
Publications in Cell Death: the golden age
- BiologyCell Death and Differentiation
Apoptosis or Programmed Cell Death has been among the fastest growing fields in the last decade. Indeed, the number of publications has increased from fewer than 100 in 1990 to over 13 000 in 2000,…
The relationship of acute mesodermal cell death to the teratogenic effects of 7-OHM-12-MBA in the foetal rat.
- Biology, MedicineBritish Journal of Cancer
ImagesFig. 1Fig. 2Fig. 3Fig. 4
A suggested explanation for the paradoxically slow growth rate of basal‐cell carcinomas that contain numerous mitotic figures
- Biology, MedicineThe Journal of pathology
Lysosome changes in acute liver injury due to heliotrine.
- MedicineThe Journal of pathology and bacteriology
An electron‐microscope study of liver cell necrosis due to heliotrine
- MedicineThe Journal of pathology