History of dementia and dementia in history: An overview

  title={History of dementia and dementia in history: An overview},
  author={François Boller and Margaret M. Forbes},
  journal={Journal of the Neurological Sciences},
History of dementia.
  • F. Boller
  • Biology
    Handbook of clinical neurology
  • 2008
Chapter 8 – Dementias
Is aging part of Alzheimer's disease, or is Alzheimer's disease part of aging?
Neuropathological Basis of Alzheimer’s Disease and Alzheimer’s Disease Diagnosis
Recent advances in the neuropathologic basis of Alzheimer’s disease include the conceptualization and study of the preclinical phase of AD, mild cognitive impairment, mixed pathologies, and the specific roles of β-amyloid and hyperphosphorylated tau protein.
[Biomarkers of the Alzheimer's disease: concepts and clinical case].
  • J. Bier
  • Psychology
    Revue medicale de Bruxelles
  • 2013
New diagnostic criteria should allow refining diagnosis in case of dementia but also and especially before the apparition of any clinical manifestations or in cases of mild suggestive cognitive disorders, and a biomarker is presented.
Diagnosis and Treatment of Alzheimer’s Disease in Elderly and Senile Age
The article deals with the important issue of the diagnosis and treatment of Alzheimer’s disease in the elderly and senile-aged and the expansion of the diagnostic search, even in cases of full confidence in the diagnosis, to determine the possible role of other pathological processes in the origin and development of dementia.
Brain Aging and Late-Onset Alzheimer's Disease: A Matter of Increased Amyloid or Reduced Energy?
Increased amyloid in the brain of old age subjects may represent the downstream event expression of a biological system that is cooling down because of its exhaustion and not the core causative factor of late-onset dementia.
Alzheimer and his disease: a brief history
The present article discusses Alzheimer’s work in the context of his life and time and discusses the most common neurodegenerative disease with more than 25 million cases worldwide and a major medical problem nearing catastrophic levels.


Origin of the distinction between Alzheimer's disease and senile dementia
History reveals that the distinction between presenile (Alzheimer's disease) and senile dementia was originally based on anecdotal clinical observations and that competition among universities was one of the underlying determinants.
Clinical subgroups of the Alzheimer syndrome
Because the heterogeneity of AD is incontestable, it is time to reconsider the current use of the term “Alzheimer's disease,” and the term” Alzheimer syndrome” appears to be more appropriate.
The concept of subcortical and cortical dementia: Another look
A review of recent clinical, neuropathological, and neurochemical studies offers little support for this classification of dementias into cortical and subcortical forms, although adequate systematic studies have not been performed.
Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB)
This work identified progressive disabling mental impairment progressing to dementia as the central feature of DLB, and identified optimal staining methods for each of these and devised a protocol for the evaluation of cortical LB frequency based on a brain sampling procedure consistent with CERAD.
The concept of dementia
Clinical diagnosis of Alzheimer's disease
The criteria proposed are intended to serve as a guide for the diagnosis of probable, possible, and definite Alzheimer's disease; these criteria will be revised as more definitive information becomes available.
Pick complex and Pick's disease: the nosology of frontal lobe dementia, primary progressive aphasia, and corticobasal ganglionic degeneration
  • A. Kertesz
  • Psychology, Medicine
    European journal of neurology
  • 1996
Two European centres with superior access to autopsy and biopsy material have taken the lead in pursuing the entity of frontal lobe dementia (FLD) and allowed that ‘future studies may indicate there is a spectrum involving both’.
Is "subcortical dementia" a recognizable clinical entity?
Patients with Huntington's or Parkinson's disease were less intellectually impaired than those with Alzheimer's disease at each functional stage, and the neuropathological basis of dementia in these diseases may result from a combination of cortical and subcortical degeneration.
Dementia of frontal lobe type.
Comparisons of DFT and Alzheimer patients revealed qualitative differences in clinical presentation, neurological signs, profile of psychological disability, electroencephalography, single photon emission tomography and demography, which suggests DFT may be more common than is often recognised.
The concept of subcortical dementia.
The authors review the concept of subcortical dementia, specifically the dementia associated with Huntington’s disease, Parkinson's disease, and progressive supranuclear palsy, which may constitute a group of partially treatable forms of dementia.