History of Cannabis and Its Preparations in Saga, Science, and Sobriquet

  title={History of Cannabis and Its Preparations in Saga, Science, and Sobriquet},
  author={Ethan B. Russo},
  journal={Chemistry \& Biodiversity},
Cannabis sativa L. is possibly one of the oldest plants cultivated by man, but has remained a source of controversy throughout its history. Whether pariah or panacea, this most versatile botanical has provided a mirror to medicine and has pointed the way in the last two decades toward a host of medical challenges from analgesia to weight loss through the discovery of its myriad biochemical attributes and the endocannabinoid system wherein many of its components operate. 

Medical Cannabis: A plurimillennial history of an evergreen

Evidence of its use in numerous pathologic conditions especially for its anti‐inflammatory, antiseptic, and anticonvulsing properties that support the requirement to direct the present research efforts into the definitive understanding of its efficacy are reported.

Synthesis of Phytocannabinoids.

The chemistry in this chapter highlights approaches to cannabinoid total synthesis with an emphasis on the implementation of modern methods and tactics, which provide access to modified structures and enable investigations of the biology of the cannabinoid product family.

Classification of Cannabis sativa L. in Relation to Agricultural, Biotechnological, Medical and Recreational Utilization

Cannabis sativa has been utilized for millennia, primarily as a source of a stem fiber (both the plant and the fiber termed “hemp”) and a resinous intoxicant (the plant and its drug preparations

Topical Use of Cannabis sativa L. Biochemicals

Cannabis sativa L. plant is currently attracting increasing interest in cosmetics and dermatology. In this review, the biologically active compounds of hemp are discussed. Particularly the complex

Cultivation and Breeding of Cannabis sativa L. for Preparation of Standardized Extracts for Medicinal Purposes

This review gives an overview of Cannabis classification, the current verities, botanical features, genomics, chemicals constituents, cellular site and biosynthesis of cannabinoids, and some aspects of current approved Cannabis based medicine and its ways of administration.

Cannabis : A Prehistoric Remedy for the Deficits of Existing and Emerging Anticancer Therapies

This review summarizes the historical perspective of C. sativa, its potential mechanism of action, and pharmacokinetic and pharmacodynamic aspects of cannabinoids, with special emphasis on their anticancer potentials.

History of Cannabis

Cannabis is one of the most omnipresent plants in the world and has been cultivated by mankind for thousands of years. Despite its near ubiquitous use throughout human history, it is considered a

Current Status and Future of Cannabis Research

Certain botanical and pharmacologic factors that complicate the collection and interpretation of clinical data on the efficacy of cannabinoid therapies are reviewed.

Cannabis-Derived Pharmaceuticals

The medicinal properties of Cannabis are reviewed and pharmaceutical-derived Cannabis products that are currently being developed for the US market are described.

Role of Cannabinoids in Pain Management

It is a curious fact that the authors owe a great deal of their insight into pharmacological treatment of pain to the plant world, and the more recent discovery of the body’s own cannabis-like system, the endocannabinoid system (ECS), which modulates pain under physiological conditions.



The Therapeutic Use of Cannabis sativa (L.) in Arabic Medicine

The therapeutic uses of the plant in Arabic medicine from the 8th to the 18th century is reviewed, finding that Arab physicians knew and used its diuretic,Anti-emetic, anti-epileptic, pro-inflammatory, painkilling and antipyretic properties, among others.

Anhydrocannabisativine, a new alkaloid from Cannabis sativa L.

Ethanol extracts of the leaves and roots of a Mexican variant of Cannabis sativa L. (marijuana) afforded the new spermidine alkaloid, anhydrocannabisativine, which was determined by spectral analysis and semisynthesis.


There can be no progress in unravelling the taxonomic complexities in the genus until the biology of the wild populations is investigated, because of the extraordinary plasticity and variability of cultivated cannabis.

The Medicinal Uses of Cannabis and Cannabinoids

Cannabis Treatments in Obstetrics and Gynecology: A Historical Review

The author believes that cannabis extracts may represent an efficacious and safe alternative for treatment of a wide range of conditions in women including dysmenorrhea, dysuria, hyperemesis gravidarum, and menopausal symptoms.

Pharmacy in medieval Islam and the history of drug addiction.

A history of their spread and consumption and the social, economic, political and medical consequences of their misuse is sketched and it is hoped to sketch a history of these two plants in medieval Islam.

Cannabis in India: ancient lore and modern medicine

India is a land steeped in faith and mysticism. Ayurveda, combining the Sanskrit words for life and knowledge, is a system of medicine intertwined inextricably with these traits. That a core of