History and future of growth hormone research.

  title={History and future of growth hormone research.},
  author={John J. Kopchick},
  journal={Hormone research},
  volume={60 Suppl 3},
The understanding of the mechanisms of growth hormone (GH) action has seen great accomplishments over the last two decades. These achievements include the cloning of a variety of GH and GH receptor (GHR) genes and cDNAs; solving of the three-dimensional structure of GH and the GH/GHR complex, and the discovery of GH antagonists. These GH antagonists have… CONTINUE READING