Historical review: Opioid receptors.

@article{Snyder2003HistoricalRO,
  title={Historical review: Opioid receptors.},
  author={S. Snyder and G. Pasternak},
  journal={Trends in pharmacological sciences},
  year={2003},
  volume={24 4},
  pages={
          198-205
        }
}
A historical review of the early phases of molecular investigations of opioid receptors is presented. The 'modern' era of molecular studies of neurotransmitter and drug receptor research commenced in the 1970s with the identification of receptors using ligand binding techniques. These findings had several ramifications. Reversible ligand binding to opioid receptors using simple, sensitive and specific techniques provided a paradigm for the study of receptors for the principal neurotransmitters… Expand
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