Historical perspectives on psychosis risk

  title={Historical perspectives on psychosis risk},
  author={Cristina Mei and Patrick D. McGorry},
1 Citations


Early detection of schizophrenia: current evidence and future perspectives.
  • H. Häfner, K. Maurer
  • Psychology, Medicine
    World psychiatry : official journal of the World Psychiatric Association
  • 2006
The aim of early recognition by the instruments discussed in this paper is to permit the identification of the largest possible proportion of at-risk persons as early as possible and their referral to appropriate treatment.
The Initial Prodrome in Psychosis: Descriptive and Qualitative Aspects
  • A. Yung, P. McGorry
  • Psychology, Medicine
    The Australian and New Zealand journal of psychiatry
  • 1996
The ground work has been laid for the development of better methodologies for assessing and measuring first psychotic prodromes with increased emphasis on experiential phenomena, which has the potential to lead to the early recognition and more accurate prediction of subsequent psychosis.
Developing psychosis and its risk states through the lens of schizotypy.
18 prospective studies on 15 samples examining the evidence for a link between trait schizotypy and conversion to psychosis in 4 different types of samples are reviewed, underline the value of schizotypesy in high-risk research, but also point to the lack of evidence needed to better define the position of the construct of schzotypy within a developmental psychopathology perspective of emerging psychosis and schizophrenia-spectrum disorders.
Diagnosing Schizophrenia in the Initial Prodromal Phase
The Bonn Scale for the Assessment of Basic Symptoms operationalization of prodromal symptoms performed well in the early detection of schizophrenia and might be useful for the prediction of the disorder, especially if it is further refined to select those items with particularly high prognostic accuracy.
The prodromal phase of first-episode psychosis: past and current conceptualizations.
This article proposes an alternative model for conceptualizing prodromal changes (the hybrid/interactive model) and discusses the different ways to view this phase of first-episode psychosis.
Is the Clinical High-Risk State a Valid Concept? Retrospective Examination in a First-Episode Psychosis Sample.
Most consenting patients with an FEP had experienced previous signs and symptoms consistent with a CHR state prior to the onset of threshold-level psychotic symptoms, although a substantial minority had not.
Early intervention in psychosis: concepts, evidence and future directions
A broader focus for early intervention would solve many of the second order issues raised by the early psychosis reform process, such as diagnostic uncertainty despite a clear-cut need for care, stigma and engagement, and should be more effective in mobilizing community support.
EPPIC: an evolving system of early detection and optimal management.
A framework for preventive intervention in early psychosis is outlined, based on more than a decade of experience initially gained within a first-generation model, a comprehensive "real-world" model of care targeting the multiple clinical foci underpinning the preventive task.
Beyond the “at risk mental state” concept: transitioning to transdiagnostic psychiatry
Findings from this and related paradigms indicate the need to develop new identification and diagnostic strategies, and a holistic strategy can be developed that applies these new prediction approaches, as well as machine learning and iterative probabilistic multimodal models, to a blend of subjective psychological data, physical disturbances and biomarkers acquired through fine‐grained sequential or longitudinal assessments.
Establishing the onset of psychotic illness.
A method for dating the first appearance of prodromal signs of psychotic illness, the emergence of an acute episode, and the initiation of treatment seeking is described.