Historical perspectives on psychosis risk

@inproceedings{Mei2020HistoricalPO,
  title={Historical perspectives on psychosis risk},
  author={Cristina Mei and Patrick D. McGorry},
  year={2020}
}
1 Citations

References

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TLDR
The aim of early recognition by the instruments discussed in this paper is to permit the identification of the largest possible proportion of at-risk persons as early as possible and their referral to appropriate treatment.
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TLDR
The Bonn Scale for the Assessment of Basic Symptoms operationalization of prodromal symptoms performed well in the early detection of schizophrenia and might be useful for the prediction of the disorder, especially if it is further refined to select those items with particularly high prognostic accuracy.
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TLDR
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TLDR
Most consenting patients with an FEP had experienced previous signs and symptoms consistent with a CHR state prior to the onset of threshold-level psychotic symptoms, although a substantial minority had not.
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A broader focus for early intervention would solve many of the second order issues raised by the early psychosis reform process, such as diagnostic uncertainty despite a clear-cut need for care, stigma and engagement, and should be more effective in mobilizing community support.
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TLDR
A framework for preventive intervention in early psychosis is outlined, based on more than a decade of experience initially gained within a first-generation model, a comprehensive "real-world" model of care targeting the multiple clinical foci underpinning the preventive task.
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TLDR
Findings from this and related paradigms indicate the need to develop new identification and diagnostic strategies, and a holistic strategy can be developed that applies these new prediction approaches, as well as machine learning and iterative probabilistic multimodal models, to a blend of subjective psychological data, physical disturbances and biomarkers acquired through fine‐grained sequential or longitudinal assessments.
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TLDR
A method for dating the first appearance of prodromal signs of psychotic illness, the emergence of an acute episode, and the initiation of treatment seeking is described.
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