375 Citations
Predominant mania course in Indian patients with bipolar I disorder.
- PsychologyAsian journal of psychiatry
- 2016
Pharmacological management of bipolar depression
- Psychology, MedicineActa psychiatrica Scandinavica
- 2002
For most bipolar patients the cornerstone of treatment is long-term prophylaxis with one or more mood stabilizers and lithium is the gold standard mood stabilizer with proven efficacy in the prevention of mania and depression.
Recurrence of bipolar disorders and major depression
- Psychology, MedicineEuropean archives of psychiatry and clinical neuroscience
- 2003
The results support lifelong prophylactic treatment of severe types of mood disorders if long-term trials confirm its efficacy, and indicate a constant risk of recurrence over the life-span up to the age of 70 or more.
Course and outcome of bipolar I disorder among Indian patients: A retrospective life-chart study
- Psychology, MedicineIndian journal of psychiatry
- 2022
A more benign presentation in the current study including Indian studies is indicated by their later age of presentation and illness onset, higher rates of marriage, education, and employment, a mania predominant course, lower rates of rapid cycling, comorbidity, and suicidal attempts.
Longitudinal course of bipolar I disorder: duration of mood episodes.
- Psychology, MedicineArchives of general psychiatry
- 2010
The median duration of bipolar I mood episodes was 13 weeks, and the probability of recovery was significantly decreased for cycling episodes, mood episodes with severe onset, and subjects with greater cumulative morbidity.
Recurrence of bipolar disorders and major depression
- Psychology, MedicineEuropean Archives of Psychiatry and Clinical Neuroscience
- 2003
The life-long recurrence risk of bipolar I, bipolar II and major depressive disorders is described and long-term trials confirm its efficacy, supporting lifelong prophylactic treatment of severe types of mood disorders.
A prospective 4-year naturalistic follow-up of treatment and outcome of 300 bipolar I and II patients.
- Medicine, PsychologyThe Journal of clinical psychiatry
- 2014
Lithium seems to offer some advantage over other medication over the long-term treatment of bipolar I and II disorder and patients tend to relapse with the same polarity as their index episode; this emphasizes the importance of the polarity concept.
Natural course and burden of bipolar disorders.
- PsychologyThe international journal of neuropsychopharmacology
- 2003
A significant need to extend the study of the natural course of bipolar disorder in clinical samples beyond the snapshot of acute episodes to theStudy of the mid-term and long-term symptom course, associated comorbidities and the associated burden of the disease is summarized.
The course of bipolar disorder in rural India
- Medicine, PsychologyIndian journal of psychiatry
- 2006
None of the variables examined appeared to predict the total number of episodes experienced by individual patients, although rapid-cycling occurred significantly more often if the patients had not received any psychopharmacological treatment.
Bipolar disorder: historic perspective, current pharmacologic treatment options and a review of quetiapine
- Psychology, MedicineExpert review of neurotherapeutics
- 2006
Quetiapine, an atypical antipsychotic, is approved by the US Food and Drug Administration for use as monotherapy or as adjunctive therapy with other mood stabilizers for the treatment of acute manic episodes of bipolar I disorder.
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- Psychology, MedicineThe Journal of clinical psychiatry
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- PsychologyPsychological Medicine
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Though all three groups exhibited similar times to recovery from index and subsequent major depressive episodes, both bipolar groups had substantially higher relapse rates and developed more episodes of major depression, hypomania and mania.
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- Psychology, MedicineJournal of affective disorders
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The interest in studies on the course of affective disorders has greatly increased as a spin-off of the introduction of long-term medication and prophylaxis as well as from the therapeutic point of view.
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- Medicine, PsychologyArchives of general psychiatry
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- Psychology, MedicineThe American journal of psychiatry
- 1995
Many contemporary bipolar patients demonstrate gradual improvement in the first several years after hospitalization, however, a subgroup approaching 60% still experience poor posthospital adjustment in one or more areas of functioning.
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- Psychology, MedicineThe Tohoku journal of experimental medicine
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Recurrence in affective disorder
- Medicine, PsychologyBritish Journal of Psychiatry
- 1998
The course of severe unipolar and bipolar disorder seems to be progressive in nature despite the effect of treatment, and the rate of recurrence after successive episodes was the same for the two disorders.
Manic‐depressive (bipolar) disorder: the course in light of a prospective ten‐year follow‐up of 131 patients
- Psychology, MedicineActa psychiatrica Scandinavica
- 1994
The patients whose alcoholism predated the onset of their affective illness were less likely to have episodes in the follow‐up than the patients in whom affective Illness predatedThe onset of the alcoholism.
Bipolar I affective disorder: predictors of outcome after 15 years.
- Psychology, MedicineJournal of affective disorders
- 1998