Historical perspectives and natural history of bipolar disorder

@article{Angst2000HistoricalPA,
  title={Historical perspectives and natural history of bipolar disorder},
  author={J. Angst and R. Sellaro},
  journal={Biological Psychiatry},
  year={2000},
  volume={48},
  pages={445-457}
}
A review of two centuries' literature on the natural history of bipolar disorder, including modern naturalistic studies and new data from a lifelong follow-up study of 220 bipolar patients, reaches the following conclusions: the findings of modern follow-up studies are closely compatible with those of studies conducted before the introduction of modern antidepressant and mood-stabilizing treatments. Bipolar disorder has always been highly recurrent and considered to have a poor prognosis… Expand
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