Historical perspective of cell transplantation in Parkinson’s disease

Abstract

Cell grafting has been considered a therapeutic approach for Parkinson's disease (PD) since the 1980s. The classical motor symptoms of PD are caused by the loss of dopaminergic neurons in the substantia nigra pars compacta, leading to a decrement in dopamine release in the striatum. Consequently, the therapy of cell-transplantation for PD consists in… (More)
DOI: 10.5500/wjt.v7.i3.179

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