Historical aspects of botulinum toxin

  title={Historical aspects of botulinum toxin},
  author={F. Erbguth and M. Naumann},
  pages={1850 - 1850}
  • F. Erbguth, M. Naumann
  • Published 1999
  • Medicine
  • Neurology
  • In recent years, the molecular mode of action of the neurotoxins produced by different strains of Clostridium botulinum has been successfully elucidated.1,2 Simultaneously, botulinum toxin type A has proved to be effective and safe in the treatment of conditions caused by focal contractions of skeletal muscles, such as strabismus, hemifacial spasm, focal dystonias, spasticity, and some autonomic disorders.3-11 Therapeutic chemodenervation with botulinum toxin was pioneered by Alan B. Scott in… CONTINUE READING
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