Historical aspects of botulinum toxin

@article{Erbguth1999HistoricalAO,
  title={Historical aspects of botulinum toxin},
  author={F. Erbguth and M. Naumann},
  journal={Neurology},
  year={1999},
  volume={53},
  pages={1850 - 1850}
}
  • F. Erbguth, M. Naumann
  • Published 1999
  • Medicine
  • Neurology
  • In recent years, the molecular mode of action of the neurotoxins produced by different strains of Clostridium botulinum has been successfully elucidated.1,2 Simultaneously, botulinum toxin type A has proved to be effective and safe in the treatment of conditions caused by focal contractions of skeletal muscles, such as strabismus, hemifacial spasm, focal dystonias, spasticity, and some autonomic disorders.3-11 Therapeutic chemodenervation with botulinum toxin was pioneered by Alan B. Scott in… CONTINUE READING
    140 Citations
    Botulinum neurotoxins: more and more diverse and fascinating toxic proteins.
    • M. Popoff
    • Biology, Medicine
    • The Journal of infectious diseases
    • 2014
    • 24
    • Highly Influenced
    • PDF
    The History of Botulinum Toxins in Medicine: A Thousand Year Journey.
    • S. Whitcup
    • Medicine
    • Handbook of experimental pharmacology
    • 2019
    • 3
    From poison to remedy: the chequered history of botulinum toxin
    • F. Erbguth
    • Medicine
    • Journal of Neural Transmission
    • 2007
    • 104
    Development of botulinum toxin therapy.
    • 44
    Botulinum Toxin for Headache
    Current Concepts in Botulism: Clinical and Electrophysiological Aspects

    References

    SHOWING 1-10 OF 24 REFERENCES
    Therapeutic uses of botulinum toxin.
    • 748
    Crystal structure of botulinum neurotoxin type A and implications for toxicity
    • 651
    Intrasphincteric botulinum toxin for the treatment of achalasia.
    • 495
    Botulinum neurotoxin A selectively cleaves the synaptic protein SNAP-25
    • 1,083
    Treatment of gustatory sweating with botulinum toxin
    • 110