Historical aspects of botulinum toxin
@article{Erbguth1999HistoricalAO, title={Historical aspects of botulinum toxin}, author={F. Erbguth and M. Naumann}, journal={Neurology}, year={1999}, volume={53}, pages={1850 - 1850} }
In recent years, the molecular mode of action of the neurotoxins produced by different strains of Clostridium botulinum has been successfully elucidated.1,2 Simultaneously, botulinum toxin type A has proved to be effective and safe in the treatment of conditions caused by focal contractions of skeletal muscles, such as strabismus, hemifacial spasm, focal dystonias, spasticity, and some autonomic disorders.3-11 Therapeutic chemodenervation with botulinum toxin was pioneered by Alan B. Scott in… CONTINUE READING
Figures and Topics from this paper
Figures
Paper Mentions
Blog Post
140 Citations
Molecular targets of botulinum toxin serotypes A and C: an experimental in-vitro and in-vivo study
- Medicine
- 2016
- PDF
Botulinum neurotoxins: more and more diverse and fascinating toxic proteins.
- Biology, Medicine
- The Journal of infectious diseases
- 2014
- 24
- Highly Influenced
- PDF
The History of Botulinum Toxins in Medicine: A Thousand Year Journey.
- Medicine
- Handbook of experimental pharmacology
- 2019
- 2
From poison to remedy: the chequered history of botulinum toxin
- Medicine
- Journal of Neural Transmission
- 2007
- 102
Current Concepts in Botulism: Clinical and Electrophysiological Aspects
- Medicine
- Journal of clinical neuromuscular disease
- 2003
References
SHOWING 1-10 OF 24 REFERENCES
Botulinum toxin in the treatment of neurological disorders of the autonomic nervous system.
- Biology, Medicine
- Archives of neurology
- 1999
- 56
- PDF
Crystal structure of botulinum neurotoxin type A and implications for toxicity
- Chemistry, Medicine
- Nature Structural Biology
- 1998
- 649
Focal hyperhidrosis: effective treatment with intracutaneous botulinum toxin.
- Medicine
- Archives of dermatology
- 1998
- 231
- PDF
Intrasphincteric botulinum toxin for the treatment of achalasia.
- Medicine
- The New England journal of medicine
- 1995
- 495
Botulinum neurotoxin A selectively cleaves the synaptic protein SNAP-25
- Biology, Medicine
- Nature
- 1993
- 1,082
Sialorrhea in amyotrophic lateral sclerosis: a hypothesis of a new treatment--botulinum toxin A injections of the parotid glands.
- Medicine
- Medical hypotheses
- 1997
- 140
Treatment of spasticity with botulinum toxin: A double‐blind study
- Medicine
- Annals of neurology
- 1990
- 399