Historical article: Titration studies and the structure of DNA.


During the period of 1946-1956 ideas on the structure of the nucleic acids, especially DNA, were profoundly influenced by physico-chemical studies and, in particular, by electrometric titration studies pioneered by J. Masson Gulland and D.O. Jordan. It was eventually conclusively inferred when such studies had been sufficiently refined that: in DNA, the… (More)


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