Historical and current perspectives on Clostridium botulinum diversity.

  title={Historical and current perspectives on Clostridium botulinum diversity.},
  author={Theresa J. Smith and Karen K. Hill and Brian H Raphael},
  journal={Research in microbiology},
  volume={166 4},
For nearly one hundred years, researchers have attempted to categorize botulinum neurotoxin-producing clostridia and the toxins that they produce according to biochemical characterizations, serological comparisons, and genetic analyses. Throughout this period the bacteria and their toxins have defied such attempts at categorization. Below is a description of both historic and current Clostridium botulinum strain and neurotoxin information that illustrates how each new finding has significantly… CONTINUE READING
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