Histopathology of necrobiotic xanthogranuloma with paraproteinemia.

  title={Histopathology of necrobiotic xanthogranuloma with paraproteinemia.},
  author={M C Finan and Richard K. Winkelmann},
  journal={Journal of cutaneous pathology},
  volume={14 2},
Fifty-three cutaneous biopsies from 22 patients with necrobiotic xanthogranuloma (NXG) were reviewed. One or more biopsies from each patient displayed a typical pattern of palisading histiocytic xanthogranuloma with bands of hyaline necrobiosis. Multiple foam cells and Touton giant cells were present, and atypical, bizarre-appearing foreign body giant cells were characteristic. Cholesterol clefts were found in 18 specimens, and lymphoid nodules were found in 24, 8 of which had germinal center… CONTINUE READING
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