Histopathology of gastrointestinal neuroendocrine neoplasms

@inproceedings{Hirabayashi2013HistopathologyOG,
  title={Histopathology of gastrointestinal neuroendocrine neoplasms},
  author={Kenichi Hirabayashi and Giuseppe Zamboni and Takayuki Nishi and Akira Tanaka and Hiroshi Kajiwara and Naoya Nakamura},
  booktitle={Front. Oncol.},
  year={2013}
}
Gastrointestinal neuroendocrine neoplasms (GI-NENs) arise from neuroendocrine cells distributed mainly in the mucosa and submucosa of the gastrointestinal tract. In 2010, the World Health Organization (WHO) classification of NENs of the digestive system was changed, categorizing these tumors as grade 1 neuroendocrine tumor (NET), grade-2NET, neuroendocrine carcinoma (large- or small-cell type), or mixed adenoneuroendocrine carcinoma (MANEC). Such a classification is based on the Ki-67 index and… CONTINUE READING
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