Histopathology and serial, multimodal magnetic resonance imaging in a multiple sclerosis variant

@article{Lindquist2007HistopathologyAS,
  title={Histopathology and serial, multimodal magnetic resonance imaging in a multiple sclerosis variant},
  author={Sabine Lindquist and Nils Christian Bodammer and Joern Kaufmann and Fatima Barbara K{\"o}nig and Hans-Jochen Heinze and Wolfgang Br{\"u}ck and Michael Sailer},
  journal={Multiple Sclerosis},
  year={2007},
  volume={13},
  pages={471 - 482}
}
Defining tools in magnetic resonance imaging (MRI) representing specific pathological processes is needed to understand the complex relationship between inflammation, myelin breakdown, axonal injury and clinical symptoms in multiple sclerosis (MS) and its variants. Here, we describe a case of histologically-defined MS, in which the radiological appearance of the lesion and clinical course support the diagnosis of Balo's concentric sclerosis. Serial magnetization transfer, diffusion tensor… 
Grey matter pathology in multiple sclerosis : in vivo and post mortem magnetic resonance imaging studies
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Atypical Inflammatory Demyelinating Syndromes of the Central Nervous System
  • T. Hardy
  • Medicine
    Contemporary Clinical Neuroscience
  • 2019
TLDR
The difficulties in diagnosing and distinguishing between conditions such as acute disseminated encephalomyelitis, tumefactive demyelination, Balo’s concentric sclerosis, Marburg's multiple sclerosis, and Schilder's diffuse myelinoclastic sclerosis are discussed.
Balo’s concentric sclerosis in a patient with spontaneous remission based on magnetic resonance imaging: A case report and review of literature
TLDR
The neurological lesion of the patient was similar to the magnetic resonance imaging and clinical findings of the BCS and a mass lesion with concentric rings adjacent to the left lateral ventricle and the posterior portion of the corpus callosum with peripheral vasogenic edema was presented.
Balò's concentric sclerosis presenting with benign clinical course and multiple sclerosis-like lesions on magnetic resonance images.
TLDR
A patient with BCS from mainland China diagnosed on magnetic resonance imaging findings showed multiple small white matter lesions in both the hemispheres and had a benign prognosis during a follow-up period of two years.
Mitochondrial defects in acute multiple sclerosis lesions
TLDR
Analysis of mitochondrial respiratory chain proteins in active lesions from acute multiple sclerosis and from WMS using immunohistochemistry suggests that hypoxia-like tissue injury in Pattern III multiple sclerosis lesions may be due to mitochondrial impairment.
Baló's concentric sclerosis
Neuronal injury in chronic CNS inflammation.
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