Histopathology and immunohistochemistry in distinguishing Burkitt lymphoma from diffuse large B-cell lymphoma with very high proliferation index and with or without a starry-sky pattern: a comparative study with EBER and FISH.

@article{Chuang2007HistopathologyAI,
  title={Histopathology and immunohistochemistry in distinguishing Burkitt lymphoma from diffuse large B-cell lymphoma with very high proliferation index and with or without a starry-sky pattern: a comparative study with EBER and FISH.},
  author={Shih-Sung Chuang and Hongtao Ye and Ming-Qing Du and C. -T. Lu and A. Latif Dogan and P P Hsieh and Wan-Ting Huang and Yun-Chih Jung},
  journal={American journal of clinical pathology},
  year={2007},
  volume={128 4},
  pages={558-64}
}
Burkitt lymphoma (BL) is characterized by c-myc translocation and CD10+/bc-2-/bcl-6+ with a very high Ki-67 proliferation index (PI). Occasional diffuse large B-cell lymphomas may exhibit a very high PI with or without a starry-sky pattern (DLBCL-HPSS). We compared 28 consecutive BL and 16 DLBCL-HPSS cases in immunocompetent Taiwanese diagnosed by histopathologic examination and immunophenotyping and compared the results with results for Epstein-Barr virus-encoded messenger RNA (EBER) and… CONTINUE READING

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