Histopathology and host response associated with reduced tumorigenicity of 5-bromodeoxyuridine--treated murine melanoma cells.

Abstract

Growth of B16 murine melanoma cells (clone B559) with low concentrations of 5-bromodeoxyuridine (BrdUrd) has previously been shown to have little effect upon cell proliferation in culture but to significantly reduce the tumorigenicity of the cells when they are injected into adult syngeneic mice. To determine the fate of BrdUrd-grown cells in vivo, we… (More)

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