Histopathological validation of a three-dimensional magnetic resonance spectroscopy index as a predictor of tumor presence.

@article{Mcknight2002HistopathologicalVO,
  title={Histopathological validation of a three-dimensional magnetic resonance spectroscopy index as a predictor of tumor presence.},
  author={Tracy R Mcknight and Mary H von dem Bussche and Daniel B. Vigneron and Ying Lu and Mitchel S. Berger and Michael W. Mcdermott and W P Dillon and Edward E Graves and Andrea Pirzkall and Sarah J. Nelson},
  journal={Journal of neurosurgery},
  year={2002},
  volume={97 4},
  pages={794-802}
}
OBJECT Data obtained preoperatively from three-dimensional (3D)/proton magnetic resonance (MR) spectroscopy were compared with the results of histopathological assays of tissue biopsies obtained during surgery to verify the sensitivity and specificity of a choline-containing compound-N-acetylaspartate index (CNI) used to distinguish tumor from nontumorous tissue within T2-hyperintense and contrast-enhancing lesions of patients with untreated gliomas. The information gleaned from the biopsy… CONTINUE READING