Histopathological findings of renal tissue induced by oxidative stress due to different concentrations of fluoride

@article{Luo2017HistopathologicalFO,
  title={Histopathological findings of renal tissue induced by oxidative stress due to different concentrations of fluoride},
  author={Qin Luo and H. Cui and H. Deng and Ping Kuang and H. Liu and Y. Lu and J. Fang and Z. Zuo and J. Deng and Yinglun Li and X. Wang and Ling Zhao},
  journal={Oncotarget},
  year={2017},
  volume={8},
  pages={50430 - 50446}
}
It has been reported that excessive intake of fluoride can induce renal lesions. However, its pathogenesis is still less understood. Therefore, this study was conducted to investigate oxidative damage and the relationships between the oxidative damage and renal lesions in fluoride-treated mice by using the methods of histopathology, biochemistry, flow cytometry and quantitative real-time polymerase chain reaction (qRT-PCR). A total of 240 ICR mice were randomly divided into four equal groups… Expand
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